|
Symbol Name ID |
Actc1
actin, alpha, cardiac muscle 1 MGI:87905 |
| Darker colors indicate more annotations |
| Human Phenotypes | Cardiomyocyte hypertrophy |
Atrial septal defect |
Secundum atrial septal defect |
Subaortic ventricular septal bulge |
Left ventricular hypertrophy |
Left ventricular noncompaction |
Dilated cardiomyopathy |
Hypertrophic cardiomyopathy |
Restrictive cardiomyopathy |
Interstitial cardiac fibrosis |
Myofiber disarray |
Increased left ventricular end-diastolic volume |
Cardiac arrest |
Palpitations |
Atrial flutter |
Ventricular tachycardia |
Ventricular arrhythmia |
Ventricular fibrillation |
Left bundle branch block |
Left anterior fascicular block |
Right bundle branch block |
Angina pectoris |
Congestive heart failure |
Syncope |
| Disease(s) Associated with ACTC1 | ||||||||||||||||||||||||
| atrial heart septal defect 5 | ||||||||||||||||||||||||
| dilated cardiomyopathy 1R | ||||||||||||||||||||||||
| hypertrophic cardiomyopathy 11 |
| Mouse Phenotypes | abnormal myocardial fiber morphology |
myocardial fiber degeneration |
myocardial fiber disarray |
disorganized myocardium |
delayed heart development |
increased heart weight |
enlarged heart |
dilated heart left ventricle |
cardiac fibrosis |
dilated cardiomyopathy |
abnormal cardiovascular system physiology |
decreased cardiac muscle contractility |
increased heart rate |
decreased QRS amplitude |
abnormal myocardial fiber physiology |
increased cardiomyocyte apoptosis |
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| Availability | Mouse Genotype | ||||||||||||||||
| Actc1tm1Jll/Actc1tm1Jll | |||||||||||||||||
| Tg(Myh6-Actc1*R312H)307Iko/? | |||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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